34 research outputs found

    Heat Exchangers in the Aviation Engineering

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    Heat exchangers are crucial in thermal science and engineering because of their essential role across the landscape of technology, from geothermal and fossil power generation to refrigeration, desalination, and air conditioning. In the aviation engineering, they have a fundamental role especially in reducing the temperatures of the fuel and thus increasing the efficiency of the aircraft engines. The literature on aviation heat exchangers is voluminous and continues to be updated today. Two main aspects of this class of flow systems are widely investigated: fluid flow and heat transfer performances, and criteria for evaluating those performances. In addition, the need of a smart and light equipment to be used inside a transport system is ever and ever felt. This requires a particular attention in the selection of components, for example in the engine zone, not only to reduce the weight but also to improve the whole heat transfer efficiency. With this aim, engineers focus their attention on new materials, for example porous materials, that recently have attracted researchers. The design process may be considered the heart of engineering. In this chapter, we will explore methods for the design or the choice of heat exchangers and list some practical case studies

    Small aircraft infrared radiation measurements supporting the engine airframe aero-thermal integration

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    © 2018 Budapest University of Technology and Economics. All rights reserved. The large, EU Supported ESPOSA (Efficient Systems and propulsion for Small Aircraft) project has developed new small gas turbines for small aircraft. One of the important tasks was the engine - airframe aero-thermal radiation integration that included task of minimizing the infrared radiation of the small aircraft, too. This paper discusses the factors influencing on the aircraft infrared radiation, its possible simulation and measurements and introduces the results of small aircraft infrared radiation measurements. The temperature of aircraft hot parts heated by engines were determined for validation of methodology developed and applied to engine - aircraft thermal integration

    ceftobiprole for the treatment of infective endocarditis a case series

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    Abstract Objectives Ceftobiprole is a relatively new cephalosporin with broad-spectrum activity and good tolerability. Despite its promising characteristics, to our knowledge, only two case reports, previously published also by some of us, is available concerning its administration for the treatment of infective endocarditis. Hereby we report our experience in this field. Methods All the patients with infective endocarditis treated with ceftobiprole were enrolled. Results 12 cases of endocarditis were treated with ceftobiprole, 11/12 in combination with daptomycin and 1/12 as monotherapy. Gram-positive bacteria were isolated in 12/12 patients; 3 cases were polymicrobial. Cure rate was 83% (10/12 patients). In 9/12 (75%) cases, patients were switched to ceftobiprole following failure of previous antimicrobial regimen. In 3/3 patients in which ceftobiprole was administered because of persistently positive blood culture, bacteraemia clearance was rapidly achieved. Conclusions Ceftobiprole, especially in combination, could be a promising alternative treatment for infective endocarditis

    The Need for a Specific Risk Prediction System in Native Valve Infective Endocarditis Surgery

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    The need for a specific risk score system for infective endocarditis (IE) surgery has been previously claimed. In a single-center pilot study, preliminary to future multicentric development and validation, bivariate and multivariate (logistic regression) analysis of early postoperative mortality predictors in 440 native valve IE patients were performed. Mathematical procedures assigned scores to the independent predictors emerged (AUC of the ROC curve: 0.88). Overall mortality was 9.1%. Six predictors were identified and assigned scores, including age (5–13 points), renal failure (5), NYHA class IV (9), critical preoperative state (11), lack of preoperative attainment of blood culture negativity (5), perivalvular involvement (5). Four risk classes were drawn ranging from “very low risk” (≤5 points, mean predicted mortality 1%), and to “very high risk” (≥20 points, 43% mortality). IE-specific risk stratification models are both needed, as disease-specific factors (e.g., cultures, abscess), beside the generic ones (e.g., age, renal impairment) affect mortality, and feasible

    Au pays maya des lacs et des marais recherches archéologiques et géographiques (1999-2001)

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    National audienceLes sociétés mayas des hautes terres ont connu un déclin culturel marqué à la fin du Préclassique (vers 100-250 apr. JC) au moment où, pour la plupart, les cités mayas des basses terres prenaient leur essor au début du Classique (250-300 apr. J.C.). Environ 600 ans plus tard, celles du Petén (Guatemala) étaient presque toutes abandonnées alors que celles des basses terres du nord connaissaient leur apogée jusqu'au début du Postclassique. En termes géographiques, il s'agit d'analyser l'évolution d'anthropo-systèmes formés en forêt tropicale humide de mousson, soit une des rares zones où s'est développée dans le passé une civilisation puissante, agricole et urbaine sur une longue durée. Le projet Petén nord-ouest La Joyanca a pour objet l'étude d'une communauté socio-politique de rang moyen, d'époque classique, située dans une région des basses terres jusqu'à présent quasiment inconnue du point de vue archéologique. Ce projet est particulier, d'une part car il associe une approche archéologique et géographique, cherchant à restituer l'histoire des hommes en même temps que l'histoire du milieu, d'autre part parce que l'initiative de cette recherche et son financement proviennent d'une compagnie pétrolière. Ce site de la Joyanca apporte des éléments nouveaux dans le corpus des "cités" mayas classiques des basses terres du Petén : désintégration du centre politico-religieux et des ensembles de palais, association étroite au centre, dans le temps et dans l'espace, des lieux de culte et d'un grand édifice politique complexe, faible densité de l'habitat

    ECMO for COVID-19 patients in Europe and Israel

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    Since March 15th, 2020, 177 centres from Europe and Israel have joined the study, routinely reporting on the ECMO support they provide to COVID-19 patients. The mean annual number of cases treated with ECMO in the participating centres before the pandemic (2019) was 55. The number of COVID-19 patients has increased rapidly each week reaching 1531 treated patients as of September 14th. The greatest number of cases has been reported from France (n = 385), UK (n = 193), Germany (n = 176), Spain (n = 166), and Italy (n = 136) .The mean age of treated patients was 52.6 years (range 16–80), 79% were male. The ECMO configuration used was VV in 91% of cases, VA in 5% and other in 4%. The mean PaO2 before ECMO implantation was 65 mmHg. The mean duration of ECMO support thus far has been 18 days and the mean ICU length of stay of these patients was 33 days. As of the 14th September, overall 841 patients have been weaned from ECMO support, 601 died during ECMO support, 71 died after withdrawal of ECMO, 79 are still receiving ECMO support and for 10 patients status n.a. . Our preliminary data suggest that patients placed on ECMO with severe refractory respiratory or cardiac failure secondary to COVID-19 have a reasonable (55%) chance of survival. Further extensive data analysis is expected to provide invaluable information on the demographics, severity of illness, indications and different ECMO management strategies in these patients

    Numerical Study on Mixed Convection in Ventilated Cavities with Different Aspect Ratios

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    An unsteady numerical investigation on mixed convection in a two dimensional open ended cavity with different aspect ratios is carried out. In this investigation, uniform temperature is set to the left and the right sides of the cavity while the other surfaces are adiabatic. The simulation is performed for a wide range of Reynolds numbers (Re = 100–1000) and Richardson numbers (Ri = 0.132–6.5 × 102), and various cavity aspect ratios (L/D = 0.5–4.0) and H/D = 0.1. Governing equations are solved using a cell centered finite volume code, a SIMPLE numerical projection scheme and a 2nd order accuracy. Results are presented in the form of streamlines, isothermal lines, and velocity profiles in the channel. The conclusion is that the enhancement of heat transfer rate is generated principally by the increasing Re and the assisting configuration is thermally more efficient when compared to the opposing one

    Blood transfusion after on-pump coronary artery bypass grafting: focus on modifiable risk factors

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    OBJECTIVES: Perioperative transfusions are known to increase morbidity and mortality after coronary artery bypass grafting (CABG). The aims of the study were (1) to identify the clinical profile of the patient subset at highest risk from transfusion and (2) to disclose causative relationship and dose-dependency of transfusion on hospital mortality. METHODS: A prospective observational design was employed on a cohort of 1047 consecutive patients (median age 63.2 ± 9.3, 18.8% female, 30.6% diabetics, 31.9% rgent/emergent, 15.3% with low preoperative left ventricular ejection fraction (LVEF)) who underwent on-pump isolated CABG between January 2004 and December 2007. Univariate and multivariate regression analysis and post-hoc risk stratification, by means of propensity scoring and binary segmentation, were adopted
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